Northeastern Oklahoma Agricultural and Mechanical College had its beginning in 1919 when Governor Robertson signed Senate Bill number 225 creating the Miami School of Mines.  A special Board of Regents, authorized under House Bill number 552, organized the school so that it offered only college work, largely of a scientific nature. After holding classes for a year in the Mining and Exchange Building in Miami, the institution moved to its new location on forty acres of land given by interested citizens of Miami.  The College was a school of mines until 1924, when during a special session of the legislature, the name of the school was changed to Northeastern Oklahoma Junior College and general collegiate courses were added to the curriculum.

Control of the College remained in the hands of the special Board of Regents until 1939 when Northeastern Oklahoma Junior College and the six teachers' colleges were placed under the Board of Regents for Agricultural and Mechanical Colleges . A 200 acre farm was purchased, agricultural courses were added, and shop buildings were constructed and equipped to carry on the mechanical work.

The College is fully accredited by The Higher Learning Commission and a member of the North Central Association.  It offers the Associate in Arts Degree, the Associate in Science degree, and the Associate in Applied Science, as well as numerous one and two-year certificate programs..